Date: 7 months ago   Category: Medicine

Scientists could turn aging process


Researchers have noted that experiments of this sort have been made for the first time. During work used laboratory mice. The group of scientists of the University of Alabama in Birmingham (USA) has for the first time conducted a research in the field of rejuvenation at animals at restoration of function of mitochondrions. During work experts have managed to make old mice then to rejuvenate them. Material on this subject has been published in the Cell Death & Disease magazine, Lenta.ru writes. Scientists have brought the mutation mentioning POLG gene coding enzyme a DNA polymerase scale in DNA of mitochondrions of rodents. This connection in mitochondrions is localized, and it participates in replication and a reparation of mitochondrial DNA (мтДНК). During work it has been established that damage of POLG provokes violations of functions of mitochondrions, in particular, dysfunction of oxidizing phosphorylation. It, in turn, lowers storage of energy and leads to emergence of signs of aging - wrinkles and loss of hair. As a result have introduced the additional copy of a gene of POLG with a mutation in the impregnated ovum of mice. DNA "was set in motion" and began to participate production of a polymerase in the presence of doxycycline - antibacterial medicine. This antibiotic began to be added to food of mice, and in several weeks at them signs of aging have begun to appear. After доксоциклин have excluded from food, there has come blocking of activity of the mutant copy of POLG that, in turn, has almost completely turned aging symptoms at rodents. Earlier it was reported that scientists have announced deadly threat which the loneliness can bear in itself. Also it was reported that the gene which promotes emergence of dependence on cocaine has been established. News from the Correspondent.netv of Telegram. Subscribe for our https://t.me/korrespondentnet channel

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